Hearts, third in the Premiership last season, will be in Pot 4 of seeds in the Conference League draw later on Friday.
Steven Naismith’s side had been in the Europa League play-off round but lost 2-0 on aggregate to Viktoria Plzen.
Like the Europa and Champions League tournaments, 36 teams will compete in the new league phase of the Conference League.
However, teams in the third-tier competition will play six games between September and December.
The top eight progress directly to the round of 16, the next 16 compete to join them while the bottom 12 are eliminated.